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The SIGN: A dynamic and extensible software framework for Image-Guided Therapy
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The software requirements for computer-aided navigation tools in image-guided therapy are becoming increasingly complex as a result of new possibilities in imaging and tracking hardware, novel application areas and regulatory restrictions. A new software [...]

CustusX: A Research Application for Image-Guided Therapy
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CustusX version 3 is an in-house application for research in image-guided therapy with a focus on intraoperative use and ultrasound imaging. It is built upon open source toolkits such as the Insight Toolkit (ITK), the Visualization Toolkit (VTK), Qt and [...]

A Lightweight and Portable Communication Framework for Multimodal Image-Guided Therapy
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In today’s medicine a lot of research revolves around the combination of different imaging and tracking modalities to form a new system for Image-Guided Therapy. Such systems can help to overcome shortcomings of the individual techniques or create new kinds [...]

An accessible, hands-on tutorial system for image-guided therapy and medical robotics using a robot and open-source software
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This paper describes a new open-source tutorial for image-guided therapy (IGT) and medical robotics that is both accessible and hands-on using the LEGO Mindstorms NXT (a commercially available robotics kit) and 3D Slicer (an open-source application for [...]

OpenITGLinkMUSiiC: A Standard Communications Protocol for Advanced Ultrasound Research
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Ultrasound imaging is the most popular and safe diagnostic medical imaging modality. Over the past years, a considerable number of studies have been conducted on new medical ultrasound imaging modalities such as ultrasound-based elasticity imaging, [...]

MUSiiC ToolKit 2.0: Bidirectional Real-time Software Framework for Advanced Interventional Ultrasound Research
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Ultrasound (US) imaging is a popular and convenient medical imaging modality thanks to its mobility, non-ionizing radiation, ease-of-use, and real-time acquisition. Conventional US imaging is frequently integrated with tracking systems and robotic systems in [...]

Flexible architecture and modularity requirements for image guided cardiovascular surgeries
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Research and development of image guided surgery techniques requires software that provides a high degree of flexibility, with easy access to reliable functionality for common tasks. The goal of this paper is to highlight this claim in the context of image [...]

OpenIGTLink Protocol Version 2
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In this paper, we review the technical details of new features in OpenIGTLink version 2. OpenIGTLink is a free open-source network communication protocol designed for data exchange among devices and software. Since the first release of version 1.0 protocol [...]

Simulink Libraries for Visual Programming of VTK and ITK
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We have created open-source Simulink block libraries for ITK and VTK that allow pipelines for these toolkits to be built in a visual, drag-and-drop style within MATLAB. Each block contains an instance of an ITK or VTK class. Any block connections and [...]

An open-source real-time ultrasound reconstruction system for four-dimensional imaging of moving organs
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Four-dimensional imaging is a necessary step in computer-assisted interventions (CAI) performed on moving surgical targets, such as those located within the beating heart or influenced by respiratory motion. Ultrasound (US) is often the best imaging modality [...]


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