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Simultaneous Manifold Learning and Clustering: Grouping White Matter Fiber Tracts Using a Volumetric White Matter Atlas

Deriche, Rachid, Wassermann , Demian
INRIA, Sophia-Antipolis
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Published in The MIDAS Journal - MICCAI 2008 Workshop: Manifolds in Medical Imaging: Metrics, Learning and Beyond.
Submitted by Demian Wassermann on 2008-09-12 11:59:02.

We propose a new clustering algorithm. This algorithm performs clustering and manifold learning simultaneously by using a graph-theoretical approach to manifold learning. We apply this algorithm in order to cluster white matter fiber tracts obtained fromDiffusion TensorMRI (DT-MRI) through streamline tractography. Our algorithm is able perform clustering of these fiber tracts incorporating information about the shape of the fiber and a priori knowledge as the probability of the fiber belonging to known anatomical structures. This anatomical knowledge is incorporated as a volumetric white matter atlas, in this case LONI's ICBM DTI-81